[13] Peñarol 0-2 Defensor Sporting [6] 2016-12-10 20:15
Clima: Céu Limpo Estádio: Estadio Campeon del Siglo Relvado: Céu Limpo Round: 15
Head to Head
| Uruguai - Clausura | 2016/02/21 23:00 | Peñarol v Defensor Sporting | W | 5-1 |
| Uruguai - Apertura | 2015/08/30 21:00 | Defensor Sporting v Peñarol | L | 3-1 |
| Uruguai - Clausura | 2015/03/15 20:00 | Peñarol v Defensor Sporting | W | 2-0 |
| Uruguai - Apertura | 2014/09/06 18:00 | Defensor Sporting v Peñarol | D | 0-0 |
Home History
| Uruguai - Apertura | 2016/12/03 19:30 | CA River Plate v Peñarol | L | 3-1 |
| Uruguai - Apertura | 2016/11/27 20:00 | Peñarol v Nacional de Football | L | 0-3 |
| Uruguai - Apertura | 2016/11/19 20:15 | Peñarol v Cerro | L | 1-2 |
| Uruguai - Apertura | 2016/11/13 22:15 | Racing Club de Montevideo v Peñarol | W | 2-5 |
| Uruguai - Apertura | 2016/10/29 19:00 | IA Sud America v Peñarol | W | 1-4 |
| Uruguai - Apertura | 2016/10/23 22:15 | Rampla Juniors v Peñarol | L | 1-0 |
| Uruguai - Apertura | 2016/10/15 22:15 | Peñarol v Villa Espanola | W | 2-1 |
| Uruguai - Apertura | 2016/10/09 19:00 | Danubio v Peñarol | L | 3-2 |
Away History
| Uruguai - Apertura | 2016/12/04 19:30 | Defensor Sporting v Racing Club de Montevideo | W | 2-1 |
| Uruguai - Apertura | 2016/11/26 22:15 | Defensor Sporting v Danubio | D | 0-0 |
| Uruguai - Apertura | 2016/11/20 22:15 | Defensor Sporting v Nacional de Football | W | 3-2 |
| Uruguai - Apertura | 2016/11/12 19:00 | Villa Espanola v Defensor Sporting | D | 2-2 |
| Uruguai - Apertura | 2016/10/29 19:00 | Rampla Juniors v Defensor Sporting | W | 0-1 |
| Uruguai - Apertura | 2016/10/23 19:00 | Plaza Colonia v Defensor Sporting | W | 0-1 |
| Uruguai - Apertura | 2016/10/16 19:00 | Defensor Sporting v Liverpool Montevideo | L | 1-3 |
| Uruguai - Apertura | 2016/10/09 19:00 | Atletico Fenix Montevideo v Defensor Sporting | L | 3-1 |