| Panamá - Liga Prom | 2021/04/14 23:00 | Panama City FC v Sporting San Miguelito - Reservas | L | 2-0 |
| Panamá - Liga Prom | 2021/10/09 21:00 | Potros del Este - Reservas v Sporting San Miguelito - Reservas | D | 0-0 |
| Panamá - Liga Prom | 2021/10/02 22:00 | Plaza Amador - Reservas v Sporting San Miguelito - Reservas | W | 0-1 |
| Panamá - Liga Prom | 2021/09/26 14:00 | Sporting San Miguelito - Reservas v San Martín FC | D | 1-1 |
| Panamá - Liga Prom | 2021/09/17 23:00 | Sporting San Miguelito - Reservas v Tauro FC - Reservas | L | 1-2 |
| Panamá - Liga Prom | 2021/09/09 21:00 | Alianza FC - Reservas v Sporting San Miguelito - Reservas | W | 2-3 |
| Panamá - Liga Prom | 2021/09/03 23:00 | Sporting San Miguelito - Reservas v Champions FC Academy | D | 0-0 |
| Panamá - Liga Prom | 2021/08/27 23:00 | Sporting San Miguelito - Reservas v Colon C-3 | D | 1-1 |
| Panamá - Liga Prom | 2021/08/21 23:00 | Sporting San Miguelito - Reservas v UMECIT | L | 0-1 |
| Panamá - Liga Prom | 2021/10/03 23:00 | Panama City FC v CD Árabe Unido - Reservas | L | 0-2 |
| Panamá - Liga Prom | 2021/09/25 21:00 | Colon C-3 v Panama City FC | L | 2-0 |
| Panamá - Liga Prom | 2021/09/19 21:00 | Champions FC Academy v Panama City FC | L | 1-0 |
| Panamá - Liga Prom | 2021/09/13 00:30 | Panama City FC v UMECIT | W | 2-1 |
| Panamá - Liga Prom | 2021/09/04 14:00 | Panama City FC v San Martín FC | D | 1-1 |
| Panamá - Liga Prom | 2021/08/30 00:00 | Panama City FC v Potros del Este - Reservas | L | 1-5 |
| Panamá - Liga Prom | 2021/08/21 23:00 | Panama City FC v Tauro FC - Reservas | L | 1-2 |
| Panamá - Liga Prom | 2021/08/14 23:00 | Plaza Amador - Reservas v Panama City FC | L | 2-0 |