[2] Boston River 0-6 Nacional de Football [9] 2022-04-10 21:30
Estádio: Estádio Parque Artigas Round: 8
Juiz: Christian Ferreyra Home Manager: Ignacio Ithurralde Away Manager: Pablo Repetto
Head to Head
| Uruguai - Clausura | 2021/10/16 21:00 | Nacional de Football v Boston River | L | 3-2 |
| Uruguai - Apertura | 2021/06/19 18:00 | Boston River v Nacional de Football | D | 1-1 |
| Uruguai - Clausura | 2021/03/25 00:15 | Nacional de Football v Boston River | W | 1-2 |
| Uruguai - Torneo Intermedio | 2020/11/29 23:00 | Boston River v Nacional de Football | L | 0-1 |
| Uruguai - Apertura | 2020/10/07 19:00 | Boston River v Nacional de Football | D | 1-1 |
| Uruguai - Clausura | 2019/10/05 19:00 | Boston River v Nacional de Football | L | 0-2 |
| Uruguai - Torneo Intermedio | 2019/08/10 21:00 | Boston River v Nacional de Football | D | 0-0 |
| Uruguai - Apertura | 2019/03/09 22:00 | Nacional de Football v Boston River | D | 2-2 |
Home History
| Uruguai - Apertura | 2022/04/02 16:15 | Albion FC v Boston River | W | 1-2 |
| Uruguai - Apertura | 2022/03/21 22:00 | Boston River v Defensor Sporting | D | 1-1 |
| Uruguai - Apertura | 2022/03/12 19:30 | Atletico Fenix Montevideo v Boston River | W | 0-2 |
| Uruguai - Apertura | 2022/02/25 20:00 | Boston River v Cerro Largo FC | W | 3-0 |
| Uruguai - Apertura | 2022/02/19 12:30 | CA River Plate v Boston River | W | 1-2 |
| Uruguai - Apertura | 2022/02/13 20:00 | Boston River v Cerrito | L | 0-1 |
| Uruguai - Apertura | 2022/02/06 20:00 | Boston River v Plaza Colonia | D | 0-0 |
| Uruguai - Clausura | 2021/12/04 20:00 | Boston River v Deportivo Maldonado | W | 2-1 |
Away History
| Copa Libertadores | 2022/04/06 22:00 | Bragantino v Nacional de Football | L | 2-0 |
| Uruguai - Apertura | 2022/04/02 21:30 | Nacional de Football v Plaza Colonia | W | 1-0 |
| Uruguai - Apertura | 2022/03/20 22:30 | Montevideo Wanderers v Nacional de Football | D | 2-2 |
| Uruguai - Apertura | 2022/03/13 22:30 | Nacional de Football v Torque | D | 1-1 |
| Uruguai - Apertura | 2022/02/27 20:00 | Peñarol v Nacional de Football | L | 1-0 |
| Uruguai - Apertura | 2022/02/21 23:15 | Nacional de Football v Liverpool Montevideo | D | 0-0 |
| Uruguai - Apertura | 2022/02/12 23:00 | Rentistas v Nacional de Football | W | 0-4 |
| Uruguai - Apertura | 2022/02/06 23:00 | Nacional de Football v Deportivo Maldonado | L | 2-3 |