[1] Club América 3-3 Santos Laguna [5] 2022-09-15 02:05
Estádio: Estadio Azteca Round: 5
Juiz: Fernando Hernandez Gomez Home Manager: Fernando Ortiz Away Manager: Eduardo Fentanes
Head to Head
| México - Liga MX | 2022/02/13 03:00 | Santos Laguna v Club América | W | 2-3 |
| México - Liga MX | 2021/10/20 00:05 | Club América v Santos Laguna | W | 2-1 |
| Europa - Amigáveis | 2021/07/05 00:30 | Club América v Santos Laguna | W | 1-0 |
| México - Liga MX | 2021/02/01 01:06 | Santos Laguna v Club América | D | 1-1 |
| México - Liga MX | 2020/08/14 02:00 | Club América v Santos Laguna | W | 3-1 |
| México - Liga MX | 2019/11/03 01:00 | Club América v Santos Laguna | L | 1-2 |
| México - Liga MX | 2019/04/28 00:00 | Club América v Santos Laguna | W | 1-0 |
| Mundo - Amigáveis de Clubes | 2018/12/29 22:30 | Club América v Santos Laguna | D | 1-1 |
Home History
| México - Liga MX | 2022/09/11 00:00 | Necaxa v Club América | W | 1-2 |
| México - Liga MX | 2022/09/07 02:05 | Club América v Atlético San Luís | W | 3-0 |
| México - Liga MX | 2022/09/04 02:05 | Club América v Tigres UANL | W | 2-1 |
| México - Liga MX | 2022/08/27 02:05 | Mazatlán FC v Club América | W | 1-3 |
| México - Liga MX | 2022/08/24 02:05 | Querétaro v Club América | W | 0-1 |
| México - Liga MX | 2022/08/21 02:05 | Club América v Cruz Azul | W | 7-0 |
| México - Liga MX | 2022/08/18 02:05 | Pachuca v Club América | W | 0-3 |
| México - Liga MX | 2022/08/14 00:05 | Pumas v Club América | W | 0-3 |
Away History
| México - Liga MX | 2022/09/10 22:00 | Querétaro v Santos Laguna | D | 3-3 |
| México - Liga MX | 2022/09/07 00:05 | Santos Laguna v Necaxa | W | 3-1 |
| México - Liga MX | 2022/09/03 22:05 | Pachuca v Santos Laguna | L | 2-0 |
| México - Liga MX | 2022/08/29 00:05 | Santos Laguna v Atlético San Luís | W | 4-1 |
| México - Liga MX | 2022/08/26 02:05 | Tijuana v Santos Laguna | W | 0-2 |
| México - Liga MX | 2022/08/21 17:00 | Pumas v Santos Laguna | W | 1-5 |
| México - Liga MX | 2022/08/19 00:00 | Santos Laguna v Club León | W | 2-1 |
| México - Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | L | 2-0 |