[9] Club León 0-3 Mazatlán FC [16] 2022-08-13 22:00
Estádio: Estádio Leon Round: 8
Juiz: Eduardo Galvan Basulto Home Manager: Renato Manuel Alves Paiva Away Manager: Gabriel Caballero
Head to Head
| México - Liga MX | 2022/03/21 03:00 | Mazatlán FC v Club León | W | 1-2 |
| México - Liga MX | 2021/08/15 00:00 | Club León v Mazatlán FC | W | 3-0 |
| México - Liga MX | 2021/04/24 02:35 | Mazatlán FC v Club León | L | 4-3 |
| México - Liga MX | 2020/10/03 02:30 | Club León v Mazatlán FC | W | 2-1 |
| Mundo - Amigáveis de Clubes | 2017/07/02 23:00 | Mazatlán FC v Club León | L | 2-1 |
| Mundo - Amigáveis de Clubes | 2016/07/10 00:00 | Club León v Mazatlán FC | L | 1-2 |
| México - Liga MX | 2016/05/15 02:06 | Club León v Mazatlán FC | W | 4-1 |
| México - Liga MX | 2016/05/12 02:00 | Mazatlán FC v Club León | D | 1-1 |
Home History
| México - Liga MX | 2022/08/07 00:00 | Monterrey v Club León | L | 5-1 |
| México - Liga MX | 2022/08/01 02:05 | Club León v Club América | W | 3-2 |
| México - Liga MX | 2022/07/27 02:05 | Club León v Toluca | L | 0-1 |
| México - Liga MX | 2022/07/21 02:05 | Chivas Guadalajara v Club León | D | 0-0 |
| México - Liga MX | 2022/07/16 00:00 | Puebla v Club León | D | 1-1 |
| México - Liga MX | 2022/07/10 00:00 | Club León v Pumas | D | 3-3 |
| México - Liga MX | 2022/07/03 22:00 | Atlético San Luís v Club León | W | 1-2 |
| Europa - Amigáveis | 2022/06/23 02:00 | Club América v Club León | L | 5-2 |
Away History
| México - Liga MX | 2022/08/06 02:05 | Mazatlán FC v Chivas Guadalajara | W | 2-1 |
| México - Liga MX | 2022/07/31 02:05 | Tijuana v Mazatlán FC | L | 2-0 |
| México - Liga MX | 2022/07/28 02:05 | Pumas v Mazatlán FC | D | 1-1 |
| México - Liga MX | 2022/07/23 00:00 | Mazatlán FC v Atlético San Luís | D | 1-1 |
| México - Liga MX | 2022/07/19 00:00 | Pachuca v Mazatlán FC | D | 1-1 |
| México - Liga MX | 2022/07/09 00:00 | Mazatlán FC v Tigres UANL | L | 0-1 |
| México - Liga MX | 2022/07/02 02:05 | Mazatlán FC v Puebla | L | 2-4 |
| México - Liga MX | 2022/05/08 22:00 | Puebla v Mazatlán FC | L | 5-3 |