[1] Lyon 3-0 Sparta de Praga [2] 2021-11-04 17:45
Estádio: Estádio Groupama Round: 4
Juiz: Maurizio Mariani Home Manager: Peter Bosz Away Manager: Pavel Vrba
Head to Head
| UEFA - Liga Europa | 2021/10/21 19:00 | Sparta de Praga v Lyon | W | 3-4 |
Home History
| França - Ligue 1 | 2021/10/30 19:00 | Lyon v Lens | W | 2-1 |
| França - Ligue 1 | 2021/10/24 11:00 | Nice v Lyon | L | 3-2 |
| UEFA - Liga Europa | 2021/10/21 19:00 | Sparta de Praga v Lyon | W | 3-4 |
| França - Ligue 1 | 2021/10/16 19:00 | Lyon v Mónaco | W | 2-0 |
| França - Ligue 1 | 2021/10/03 18:45 | St Etienne v Lyon | D | 1-1 |
| UEFA - Liga Europa | 2021/09/30 16:45 | Lyon v Brondby | W | 3-0 |
| França - Ligue 1 | 2021/09/25 19:00 | Lyon v Lorient | D | 1-1 |
| França - Ligue 1 | 2021/09/22 19:00 | Lyon v Troyes | W | 3-1 |
Away History
| República Checa - 1. Liga | 2021/10/31 14:00 | Banik Ostrava v Sparta de Praga | D | 2-2 |
| Taça da República Checa | 2021/10/27 15:00 | FK Teplice v Sparta de Praga | W | 0-2 |
| República Checa - 1. Liga | 2021/10/24 17:00 | Sparta de Praga v Mlada Boleslav | W | 1-0 |
| UEFA - Liga Europa | 2021/10/21 19:00 | Sparta de Praga v Lyon | L | 3-4 |
| República Checa - 1. Liga | 2021/10/17 17:00 | Pardubice v Sparta de Praga | W | 2-4 |
| República Checa - 1. Liga | 2021/10/03 17:00 | Sparta de Praga v Slavia Praga | W | 1-0 |
| UEFA - Liga Europa | 2021/09/30 16:45 | Sparta de Praga v Rangers | W | 1-0 |
| República Checa - 1. Liga | 2021/09/25 17:00 | FC Trinity Zlín v Sparta de Praga | W | 2-5 |